NADH 2Na (606-68-8)

March 15, 2020

NADH jẹ fọọmu ti enzymu adenine dinucleotide (NAD) nicotinamide, fọọmu coenzyme ti n ṣiṣẹ ti apopọ ati Vitamin B3 ……….

 


ipo: Ni Ifilelẹ Production
Ṣiṣẹpọ ati ki o ti adani Wa
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NADH 2Na (606-68-8) fidio

Awọn alaye Pataki Beta-Nicotinamide adenine dinucleotide iyọ (NADH 2Na)

ọja orukọ Beta-Nicotinamide adenine iyọ disodium iyọ (NADH 2Na)
Orukọ Kemikali NADH (iyọ disodium); Disodium nicotinamide adenine dinucleotide; eta-d-ribofuranosyl-3-pyridinecarboxamide, disodiumsalt; beta-NADH Disodium Salt; Nicotinamide adenine dinucleotide, dinku;
CAS Number 606-68-8
InChIKey QRGNQKGQENGQSE-WUEGHLCSSA-L
SMILE C1C=CN(C=C1C(=O)N)C2C(C(C(O2)COP(=O)([O-])OP(=O)([O-])OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O.[Na+].[Na+]
molikula agbekalẹ C21H27N7Na2O14P2
molikula iwuwo 709.4
Ibi Monoisotopic 709.088661 g / mol
Ofin Melting 140-142 ℃
Awọ Yellow
Storage iwa afẹfẹ 2-8 ℃
solubility H2O: 50 iwon miligiramu / milimita, lati ko o fẹrẹẹrẹ, ofeefee
ohun elo Ogun; ounjẹ ati awọn afikun ijẹẹmu;

 

Kini Beta-Nicotinamide adenine dinucleotide disodium iyọ (NADH 2Na)?

NADH jẹ fọọmu ti enzymu adenine dinucleotide (NAD) nicotinamide, fọọmu coenzyme ti nṣiṣe lọwọ ti idapọ ati Vitamin B3. NADH (b-Nicotinamide adenine dinucleotide) Iyọ Disodium, dinku, ti a tun mọ ni Nicotinamide adenine dinucleotide, jẹ coenzyme ninu awọn aati redox. Awọn iṣẹ rẹ bi olufunni eleda eleto ni awọn ilana iṣelọpọ pẹlu glycolysis, β-ifoyina ati ọmọ citric acid (Krebs ọmọ, iyipo TCA). Iyọyọyọ ti NADH tun jẹ alabaṣe ninu awọn iṣẹlẹ ifihan sẹẹli, fun apẹẹrẹ bi aropọ fun polymeras poly (ADP-ribose) polymerases (PARPs) lakoko idahun ibajẹ DNA. Gẹgẹbi iyọ ti ko ni nkan ti NADH, o ti lo ninu ounjẹ ati awọn afikun awọn ounjẹ ni itọju arun Arun Parkinson, iṣọn rirẹ onibaje, Arun Alzheimer ati awọn arun inu ọkan ati ẹjẹ.

 

Beta-Nicotinamide adenine iyọ disodium iyọ (NADH 2Na)

Gẹgẹbi coenzyme ti awọn iṣẹ atẹgun, iyọ NADH ainipẹkun n ṣe ipa pataki ninu iṣelọpọ agbara ti ara.

- Iyọyọyọ ti NADH le yorisi wípé ọpọlọ ti o dara julọ, titaniji, idojukọ, ati iranti. O le mu alekun ọpọlọ pọ si ati pe o le mu iṣesi pọ si. O le mu awọn ipele agbara sii ninu ara ati mu iṣelọpọ agbara, agbara ọpọlọ ati ifarada mu.

- Ran awọn eniyan lọwọ pẹlu ibanujẹ iṣegun, titẹ ẹjẹ giga tabi idaabobo awọ giga;

- Mu ilọsiwaju ṣiṣe ṣiṣe dara;

- Ṣe idaduro ilana ti ogbo ati ṣetọju iduroṣinṣin ti awọn sẹẹli nafu lati ṣe atilẹyin eto aifọkanbalẹ;

- Le ṣe itọju arun Aarun Parkinson, mu iṣẹ ti awọn iṣan ara iṣan ni ọpọlọ ti awọn alaisan ti o ni arun Parkinson, dinku ailera ara ati awọn iwulo oogun;

- Itọju onibaje rirẹ onibaje (CFS), Arun Alzheimer ati arun inu ọkan ati ẹjẹ;

- Dabobo lodi si awọn ipa ẹgbẹ ti oogun Arun Kogboogun Eedi ti a pe ni zidovudine (AZT);

- Lodi si awọn ipa oti lori ẹdọ;

- Jet lag

 

Beta-Nicotinamide adenine iyọ disodium iyọ (NADH 2Na) awọn ipa ẹgbẹ:

Ni bayi, iyọ disodium NADH dabi ailewu fun ọpọlọpọ eniyan nigbati a lo daradara ati akoko kukuru, to ọsẹ 12. Pupọ eniyan ko ni iriri eyikeyi awọn ipa ẹgbẹ nigba gbigbe iye ti a ṣe iṣeduro lojoojumọ, eyiti o jẹ 10 miligiramu.

Bibẹẹkọ, ko si iwe data ti o to nipa lilo iyọ iyọda ti NADH lakoko oyun ati igbaya-ọmu., Nitorinaa wọn yẹ ki o duro si ẹgbẹ ailewu ki o yago fun lilo.

 

Reference:

  • Birkmayer JG, Vrecko C, Volc D, Birkmayer W. Nicotinamide adenine dinucleotide (NADH) - ọna itọju tuntun si arun Parkinson. Lafiwe ti ohun elo ẹnu ati ti obi. Iṣẹ Neurol Scand Suppl 1993; 146: 32-5.
  • Budavari S, ed. Atọka Merck. Oṣu kejila 12. Ibudo Whitehouse, NJ: Merck & Co., Inc., 1996.
  • Bushehri N, Jarrell ST, Lieberman S, et al. O dinku idinku B-nicotinamide adenine dinucleotide (NADH) ni ipa lori titẹ ẹjẹ, peroxidation lipid, ati profaili lipid ni awọn eku haipatensonu (SHR). Geriatr Nephrol Urol 1998; 8: 95-100.
  • Bushehri N, Jarrell ST, Lieberman S, et al. O dinku idinku B-nicotinamide adenine dinucleotide (NADH) ni ipa lori titẹ ẹjẹ, peroxidation lipid, ati profaili lipid ni awọn eku haipatensonu (SHR). Geriatr Nephrol Urol 1998; 8: 95-100.
  • Castro-Marrero J, Cordero MD, Segundo MJ, et al. Njẹ iṣọn coenzyme Q10 pẹlu ifikun NADH mu ilọsiwaju rirẹ ati awọn aye biokemika ni aisan rirẹ onibaje? Ami Antoxid Redox 2015; 22 (8): 679-85.
  • Dizdar N, Kagedal B, Lindvall B. Itoju ti arun Parkinson pẹlu NADH. Ṣiṣẹ Neurol Scand 1994; 90: 345-7.