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Nicotinamide riboside kiloraidi (NR-CL) (23111-00-4)

Nicotinamide riboside (NR) jẹ iṣapẹẹrẹ nicotinamide tuntun adenine dinucleotide (NAD +) Vitamin iṣaju iṣaju. Awọn …….


ipo: Ni Ifilelẹ Production
Apapọ: 25kg / Ilu

Apejuwe

Nicotinamide riboside kiloraidi (NR-CL) (23111-00-4) Sawọn ilana

ọja orukọ Nicotinamide riboside kiloraidi (NR-CL) (23111-00-4)
Orukọ Kemikali NRC; 3-Carbamoyl-1-beta-D-ribofuranosylpyridinium kiloraidi; Nicotinamide ribose kiloraidi; 3-Carbamoyl-1- (β-D-ribofuranosyl) kiloraidi pyridinium; 3-carbamoyl-1 - ((2R, 3R, 4S, 5R) -3,4-dihydroxy-5- (hydroxymethyl) tetrahydrofuran-2-yl) pyridin-1-ium kiloraidi; Nicotinamide BD Riboside Chloride (WX900111); NR-CL;
CAS Number 23111-00-4
InChIKey YABIFCKURFRPPO-IVOJBTPCSA-N
SMILE C1 = CC (= C [N +] (= C1) C2C (C (C (O2) CO) O) O) C (= O) N. [Cl-]
molikula agbekalẹ C11H15ClN2O5
molikula iwuwo 290.7002
Ibi Monoisotopic 290.066949 g / mol
Ofin Melting N / A
Awọ funfun
Storage iwa afẹfẹ -20 ° C Dasita
ohun elo awọn afikun ijẹẹmu, aaye elegbogi

ohun ti o jẹ Nicotinamide riboside kiloraidi(NR-CL)?

Nicotinamide riboside (NR) jẹ iṣapẹẹrẹ nicotinamide tuntun adenine dinucleotide (NAD +) Vitamin iṣaju iṣaju. Fọọmu kirisita ti NR kiloraidi ni a pe ni NIAGEN, eyiti o jẹ fọọmu sintetiki ti nicotinamide riboside ati orisun lati eyiti nicotinamide ni irisi eroja nicotinic le jẹ bioavare ati pe gbogbo eniyan ni a ka si ailewu (GRAS). NR kiloraidi jẹ koko-ọrọ ti awọn akiyesi awọn eroja eroja titun ti ijẹẹmu meji, eyiti a lo ni awọn afikun awọn ounjẹ.

Nicotinamide Riboside Chloride jẹ eroja ti ara ti o rii wara. O ti ni ibatan gangan ni niacin ati awọn fọọmu miiran ti Vitamin B3. Diẹ ninu awọn iwadii ti rii pe Nicotinamide Riboside Chloride ni diẹ ninu awọn abuda alailẹgbẹ ti o le ṣe igbelaruge iṣelọpọ ọkan lati ṣe iranlọwọ lati sun awọn kalori diẹ sii ati ṣe idiwọ iwuwo. Ni afikun si pipadanu iwuwo, o tun ṣe iranlọwọ igbelaruge iṣẹ iṣan, mu inawo inawo pọ si, ati dinku awọn okunfa ewu ti àtọgbẹ.

Pẹlupẹlu, iwadii kan ninu eniyan ti fihan pe awọn mejeeji Nicotinamide Riboside Chloride ṣe igbega awọn ipele NAD +, eyiti o ṣe iranlọwọ lati ṣe ameliorate diẹ ninu awọn ipo ti o jọmọ ọjọ-ori, botilẹjẹpe o ti pẹ lati mọ sibẹsibẹ bawo ni yoo ṣe jẹ.

anfani ti Nicotinamide riboside kiloraidi(NR-CL)

Nicotinamide riboside kiloraidi jẹ fọọmu ti sintetiki ti nicotinamide riboside, awọn anfani rẹ / iṣẹ rẹ jẹ kanna bi nicotinamide riboside. O kopa ninu iṣelọpọ ninu ara, ni a le lo lati ṣe idiwọ pellagra tabi arun miiran ti arun niacin ati lati dinku idaabobo awọ ati triglycerides ninu ẹjẹ. A tun lo o lati dinku eegun eegun ọkan ninu awọn eniyan ti o ni idaabobo awọ giga ti wọn ti ni arun inu ọkan tẹlẹ. Nigba miiran a lo lati ṣe itọju arun iṣọn-alọ ọkan (atherosclerosis), ṣe aabo aabo ọpọlọ ati ẹdọ (arun inu ọkan, alakan, arun Alzheimer).

Yato si, Nicotinamide riboside kiloraidi tun ni awọn anfani miiran ni eniyan:

  • Walẹ deede ati gbigba ti awọn ọlọjẹ ati awọn ọra;
  • Iranlọwọ ṣe iyipada pataki tryptophan amino acid sinu niacin;
  • Din ìgbagbogbo, ati dinku awọn abajade ti mu awọn oogun apakokoro nitori ẹnu gbigbẹ ati iṣoro urin;
  • Ṣe igbelaruge iṣelọpọ eefin nucleic acid ati idiwọ ti ogbo awọn ara ati awọn ara, nitorinaa iyọrisi idi ti idaduro ti ogbo;
  • O lọra isan iṣan ti iṣan, ipọnju spastic ati ọwọ ati ẹsẹ neuritis;
  • Itoju hypometabolism ti apọju ati imudara ti iṣelọpọ;
  • Idena ati itọju ti aipe Vitamin B6;
  • Itoju ti aisan eefin carpal;
  • Ṣe iranlọwọ pipadanu iwuwo ati arawa iṣẹ iṣan.
  • Ṣe imudara ara ti ara si awọn sẹẹli alakan
  • Dena pipadanu igbọran
  • Ṣe diuretic adayeba kan.
  • Mu awọn abere ti o tobi le ṣe ifunni afẹsodi oogun ati ni ipa detoxification to dara.
  • Imudara iṣẹ ti awọn sẹẹli kẹtimiẹli, ati awọn iṣẹ ti awọn sẹẹli miiran ninu ara eniyan, lati jẹ ki awọ ara tàn.

Nicotinamide riboside kiloraidi(NR-CL) lilo

Nitori Nicotinamide riboside kiloraidi ni awọn ohun-ini oogun ti o ni anfani, a nlo igbagbogbo ni awọn afikun ounjẹ, oogun ati aaye ifunni.

Reference:

  • Conze D, Brenner C, Kruger CL. Ailewu ati Ti iṣelọpọ ti Iṣakoso akoko-gigun ti NIAGEN (Nicotinamide Riboside Chloride) ni Randomized, Afọju Meji, Ibi idanwo Iṣakoso-iwosan ti placebo ti Awọn Agbalagba Abo ilera. Sci Rep. 2019 Jul 5; 9 (1): 9772. doi: 10.1038 / s41598-019-46120-z. PMID: 31278280 PMCID: PMC6611812.
  • Bogan, KL, Brenner, C. (2008). “Nikotinic acid, nicotinamide, ati riboside nicotinamide: igbelewọn molikula ti NAD + awọn vitamin ti o jẹ ṣaaju ni ounjẹ eniyan”. Lododun. Rev. Nutr. 28: 115-130. doi: 10.1146 / annurev.nutr.28.061807.155443. PMID 18429699.
  • Chi Y, Sauve AA (Oṣu kọkanla ọdun 2013). “Nicotinamide riboside, ounjẹ ti o wa kakiri ni awọn ounjẹ, jẹ Vitamin B3 pẹlu awọn ipa lori iṣelọpọ agbara ati neuroprotection”. Itọju Curr Opin Clin Nutr Metab Abo. 16 (6): 657-61. doi: 10.1097 / MCO.0b013e32836510c0. PMID 24071780.

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