7,8-dihydroxyflavone (38183-03-8) lulú

November 26, 2021

Awọn ẹkọ-ẹkọ ti fihan pe afikun 7,8-dihydroxyflavone eyiti o ni 7,8-dihydroxyflavone lulú funfun le mu iranti dara, dinku wahala, ati atunṣe awọn iṣan ti o bajẹ.

Iwọn peptide BDNF ti o peye jẹ pataki lati ṣe idiwọ neuro-idibajẹ.Sibẹsibẹ, nitori BDNF ko ni imunadoko kọja idena-ọpọlọ ẹjẹ, o ni gbigba ti ko dara ninu ọpọlọ. O yanilenu, 7,8-dihydroxyflavone kii ṣe nikan le ṣe afiwe awọn ipa ti BDNF, ati pe O ro pe o jẹ agonist TrkB bi o ti sopọ mọ olugba Trkb ni ọna kanna bi BDNF. Awọn anfani 7,8-dihydroxyflavone miiran ko le ṣe akiyesi ni pe o le kọja idena-ọpọlọ ẹjẹ.


ipo: Ni Ifilelẹ Production
Apapọ: 25kg / Ilu
agbara: 1100kg / osù

 

7,8-DIHYDROXYFLAVONE (38183-03-8) Awọn pato

ọja orukọ 7,8-dihydroxyflavone
Orukọ Kemikali Tropoflavin;

7,8-dihydroxy-2-phenylchromen-4-ọkan;

Awọn Synonyms 7,8-dihydroxy-2-phenyl-4H-chromen-4-ọkan;

7,8-dihydroxyflavone hydrate

7,8-DHF;

4H-1-Benzopyran-4-ọkan;

7,8-Dihydroxy-flavone;

7,8-Dihydroxy-2-phenyl-chromen-4-ọkan;

7,8-Dihydroxy-2-phenyl-4-benzopyrone;

CAS Number 38183-03-8
InChIKey COCYGNDCWFKTMF-UHFFFAOYSA-N
molikula Fagbalagba C15H10O4
molikula Wmẹjọ 254.24
Ibi Monoisotopic 254.05790880
Isun ojuami  243-246 ° C
farabale ojuami 494.4 ± 45.0 ° C (Asọtẹlẹ)
Awọ Yellow lulú
fọọmù ri to
Solubility  DMSO: soluble24mg/ml
Sdidiṣi Tti otutu  Afẹfẹ inert,Iwọn otutu yara
ohun elo 7,8-dihydroxyflavone hydrate ti a ti lo bi tropomyosin-receptor-kinase B (TrkB) agonist ninu eku ati lati dojuti TrkB fun mimojuto evoked excitatory postsynaptic currents (eEPSCs).
Iwe adehun Idanwo wa

 

7,8-Dihydroxyflavone lulú - Kini 7,8-DHF? Tabi Tropoflavin?

Tropoflavin lulú tabi 7,8-dihydroxyflavone jẹ moleku kemikali kan. O fara wé awọn iṣẹ ti ọpọlọ-ti ari neurotrophic ifosiwewe (BDNF). BDNF wa ni ti ara ni ọpọlọ ati ọpa-ẹhin. BDNF ṣe ipa pataki ninu kikọ ẹkọ, imudarasi iranti, neuroplasticity eyiti o jẹ agbara lati ṣe agbekalẹ awọn ipa-ọna tuntun ati awọn asopọ, ati neurogenesis agba eyiti o jẹ agbara lati dagba awọn sẹẹli ọpọlọ tuntun ninu awọn agbalagba pẹlu awọn ọpọlọ ti o dagba ni kikun.

Tropoflavin lulú ti han lati ṣe iranlọwọ ni atunṣe ọpọlọ, iranti igba pipẹ, ibanujẹ, ati awọn aarun neurodegenerative ni orisirisi awọn iwadii ile-iwosan ati awọn idanwo ti a ṣe lori awọn eku ati awọn eku. Sibẹsibẹ, ni bayi, ko si awọn idanwo ile-iwosan tabi iwadii ti a ṣe lori eniyan. Pupọ ti ẹri ti o jẹri awọn anfani ti lulú tropoflavin ti wa lati awọn ikẹkọ ẹranko. Ẹri bii: awọn anfani ni iranti, aabo awọn sẹẹli ọpọlọ ati titọju iṣẹ ọpọlọ jẹ diẹ ninu awọn abajade rere lati ọpọlọpọ awọn iwadii ẹranko.

 

Bawo ni 7,8-Dihydroxyflavone Ṣiṣẹ? 

7,8-Dihydroxyflavone fara wé iṣẹ ṣiṣe ti ọpọlọ-ti ari neurotrophic ifosiwewe. O ṣe bẹ nipataki nipasẹ ṣiṣiṣẹ ipa ọna olugba ti a mọ si ọna awọn olugba ti o ni ibatan kinase B (TrkB) Tropomyosin. Eyi jẹ ọna kanna nipasẹ eyiti BDNF ṣiṣẹ. Yato si 7,8-DHF ti a ti ri lati ṣiṣẹ ni ominira lati pese iṣẹ-ṣiṣe antioxidant.

Awọn anfani ti o pọju ti BDNF jẹ ihamọ nipasẹ igbesi aye idaji kukuru ti o kere ju iṣẹju mẹwa 10. BDNF tun ko le rekọja idena-ọpọlọ ẹjẹ nitori iwọn nla ti moleku naa. Ni apa keji, 7,8-dihydroxyflavone le wọ inu awọn sẹẹli inu ọpọlọ ati ọpa-ẹhin nipasẹ lila idena yii. Tẹlẹ awọn iwadii ti ṣe afihan pe 7,8-DHF jẹ bioavailable orally ati pe o le wọ inu idena ọpọlọ-ẹjẹ. 7,8-dihydroxyflavone (7,8-dhf) le nitorina ṣe iranlọwọ ni imudarasi iṣẹ ọpọlọ ati ilera.

 

Kini 4′-Dimethylamino-7, 8-Dihydroxyflavone (Eutropoflavin)? 

4′-Dimethylamino-7,8-dihydroxyflavone (4'DMA-7, 8-DHF), tun npe ni eutropoflavin tabi R13 ni s, jẹ ẹya sintetiki ti 7,8-dihydroxyflavone. O jẹ apẹrẹ ti a ti yipada ati ti iṣelọpọ ti 7, 8-Dihydroxyflavone. Eutropoflavin ni igbesi aye idaji to gun kaakiri ati pe o ni agbara diẹ sii ju 7, 8-Dihydroxyflavone.

Awọn agbo ogun meji naa ni awọn ẹya kemikali kanna. 4'DMA-7, 8-DHF yipada si 7, 8-Dihydroxyflavone lakoko titan ninu ara.

Iwadii kere si lori 4′-Dimethylamino-7,8-dihydroxyflavone. Gbogbo iwadi ti o lopin ti o wa ni a ṣe lori awọn ẹranko. Ẹri ti o wa ni imọran pe 4'-Dimethylamino-7,8-dihydroxyflavone ati 7,8-Dihydroxyflavone ni awọn ọna kanna tabi iru ti iṣẹ ṣiṣe.

 

Kini 4′-DMA-7 8-dihydroxyflavone ṣe?  

4′-Dimethylamino-7,8-dihydroxyflavone tabi Eutropoflavin jẹ flavone sintetiki. O jẹ moleku kekere yiyan ti o ṣiṣẹ lori awọn olugba TrkB, olugba akọkọ ti awọn ifosiwewe neurotrophic ti ọpọlọ. Eutropoflavin ti wa lati inu igbekalẹ ati iyipada kemikali ti tropoflavin.

Ti a ṣe afiwe si tropoflavin, eutropoflavin ti han lati ni iṣẹ ti o dara julọ ni olugba TrkB. Eutropoflavin ni a rii pe o ni agbara pupọ diẹ sii ju tropoflavin ati pe o ṣe afihan iye akoko to gun ninu awọn ikẹkọ ẹranko. 4′-Dimethylamino-7,8-dihydroxyflavone ni a ti rii lati ni neuroprotective, neurogenic, ati awọn ohun-ini antidepressant ninu awọn ẹranko.

 

7,8-Dihydroxyflavone vs 4′-dma-7 8-dihydroxyflavone

Mejeeji 7,8-Dihydroxyflavone ati 4′-DMA-7 8-dihydroxyflavone ti han lati ṣe awọn abajade kanna ni awọn ikẹkọ ẹranko. Ipa naa ko tii ṣe iwadi ninu awọn idanwo eniyan.

Botilẹjẹpe awọn mejeeji jẹ awọn agbo ogun kanna, iyatọ nla ni a rii laarin iṣẹ ṣiṣe ti awọn mejeeji. Awọn idanwo ile-iwosan ati iwadii fihan pe eutropoflavin ni agbara pupọ diẹ sii ju tropoflavin ati paapaa ṣe afihan iye akoko to gun julọ.

Bii iru bẹẹ, botilẹjẹpe 7,8-dhf ati 4′-DMA-7 8-dihydroxyflavone jẹ iru kemikali ati paapaa ni awọn ipa ti o jọra, 4′-DMA-7 8-dihydroxyflavonne ni a rii pe o ni iṣe ti o lagbara pupọ ati ṣiṣẹ ni pipẹ, ni iwadi ṣe ni eranko si dede.

 

Kini idi ti Gbigba Tropoflavin lulú Ṣe Gbale Gbajumọ? 

Tropoflavin lulú tabi 7,8-Dihydroxyflavone lulú ti n gbaye-gbale. Pẹlu awọn iwadii tuntun ati awọn idanwo ile-iwosan ti n ṣafihan pẹlu awọn abajade rere, 7,8-Dihydroxyflavone lulú n jade bi koko-ọrọ ti o gbona paapaa ni agbegbe ijinle sayensi.

Ko si awọn idanwo ile-iwosan tabi iwadii ti a ṣe lori eniyan ni bayi. Sibẹsibẹ, awọn ti o ti lo 7,8-Dihydroxyflavone lulú ti sọ pe lulú ni ilọsiwaju pataki ninu wọn:

  •   Memory
  •   agbara
  •   eko
  •   iṣesi
  •   Iranti ati Imọ Support

Tropflavin lulú jẹ tun fihan pe o munadoko lati ṣe aṣeyọri iṣesi iwọntunwọnsi, nini iṣelọpọ agbara ti o dara, nini awọn ohun-ini aabo-ọpọlọ, nini awọn ohun-ini anti-oxidant ati atilẹyin awọn kokoro arun ikun.

 

7,8-Dihydroxyflavone awọn anfani ati awọn ipa - Kini 7,8-Dihydroxyflavone ṣe? 

7,8-Dihydroxyflavone lulú (7,8-dhf) ti han lati ni awọn anfani pupọ. Sibẹsibẹ, titi di oni, awọn idanwo ile-iwosan ti o lopin ati iwadii ti ṣe lori eniyan. 7,8-Dihydroxyflavone lulú ti ri pe o munadoko ninu iwadi ati idanwo ti a ṣe ni awọn awoṣe eranko ati iwadi ti o da lori sẹẹli. Awọn iwadi siwaju sii lori imunadoko ninu eniyan ni a tun nilo. Diẹ ninu awọn abajade rere lati iwadii ati awọn idanwo lori 7,8-dhf lulú lati awọn ẹkọ ẹranko ti wa ni akojọ si isalẹ:

  • Iranti ati Ẹkọ
  • Atunṣe Ọpọlọ
  • Neuroprotection
  • Alatako-Irun
  • Ipa ninu Arun Neurodegenerative
  • şuga
  • afẹsodi
  • isanraju
  • ẹjẹ Ipa
  • Ogbo awọ
  • akàn

Iranti ati Ẹkọ

7,8-Dihydroxyflavone lulú ni a ti rii lati wulo ni imudarasi iranti ati idanimọ ohun, ati idinku wahala ninu awọn eku. O tun rii pe o munadoko ni imudarasi iranti ni awọn eku ti ogbo.

 

Atunṣe Ọpọlọ

7,8-Dihydroxyflavone lulú (7,8-dhf) ni a rii pe o munadoko ninu igbega si atunṣe ti awọn sẹẹli ara ti o bajẹ, jijẹ iṣelọpọ ti awọn neuronu tuntun ninu ọpọlọ ti awọn eku agbalagba lẹhin ipalara ọpọlọ ati ni igbega idagbasoke sẹẹli nafu tuntun ni eku agba

Bakanna, 7,8-Dihydroxyflavone lulú, ni a tun rii pe o munadoko ninu imudarasi awọn iṣẹ ọpọlọ ni awọn eku ti o ti ni ipalara ti ọpọlọ.

 

Neuroprotection

7,8-Dihydroxyflavone lulú ni a rii pe o munadoko ni aabo lodi si ibajẹ ọpọlọ ti o ni ibatan ọpọlọ, paapaa ni awọn eku abo. O tun ṣe idiwọ ibajẹ sẹẹli nafu ninu awọn eku lẹhin ipalara ọpọlọ ikọlu.

 

Egboogi-Idaamu

7,8-Dihydroxyflavone lulú ti ri lati ni awọn ipa-ipalara-iredodo. O ti rii lati ni anfani lati dinku igbona ninu ọpọlọ ati awọn sẹẹli ẹjẹ funfun.

 

Ipa ninu Arun Neurodegenerative

7,8-dhf lulú ti a ti ri lati mu awọn ipa oriṣiriṣi ṣiṣẹ ni orisirisi awọn arun neurodegenerative, eyiti a sọ ni isalẹ.

 

Arun Alzheimer

Awọn awoṣe ẹranko ti ṣe afihan awọn abajade idapọpọ fun arun Alzheimer. Diẹ ninu awọn ijinlẹ ti fihan pe 7,8-Dihydroxyflavone lulú ni ipa pataki ninu idilọwọ rẹ, nigba ti awọn miiran ko ṣe afihan awọn anfani kankan. Iwadi diẹ sii ni a nilo ni agbegbe yii.

 

Arun Pakinsini

7,8-Dihydroxyflavone lulú ti a ti ri lati mu awọn iṣẹ-ṣiṣe motor ni awọn awoṣe eranko. O tun rii lati ni awọn iṣe aabo lodi si iku ti awọn neuronu. O tun ṣe idilọwọ iku ti awọn neuronu ifarabalẹ dopamine ni awọn awoṣe ọbọ ti arun Pakinsini.

 

Arun Huntington

7,8-Dihydroxyflavone lulú ti a ti ri lati pẹ awọn igbesi aye ti awọn awoṣe eranko pẹlu Arun Huntington.

 

Amyotrophic Yiyesita sclerosis (ALS)

7,8-Dihydroxyflavone lulú dara si awọn aipe motor ati iwalaaye ti o pọ si ni awọn ẹkọ ti a ṣe ni awoṣe asin pẹlu ALS.

 

ọpọ sclerosis

7,8-Dihydroxyflavone lulú dinku idibajẹ ti arun na.

 

Schizophrenia

7,8-Dihydroxyflavone lulú dara si awọn iṣẹ ikẹkọ ni awọn awoṣe eku.

 

Aisan Arun

Idawọle ni kutukutu pẹlu 7,8-Dihydroxyflavone lulú (7,8-dhf) ni a ti rii lati mu iṣelọpọ ti awọn neuronu tuntun pọ pẹlu ẹkọ ti o dara julọ ati iranti.

 

Arun X ẹlẹgẹ

Arun X ẹlẹgẹ jẹ ipo jiini. O fa ọpọlọpọ awọn iṣoro idagbasoke pẹlu ailagbara imọ ati awọn ailagbara ikẹkọ.

Ni awoṣe asin ti ailera X ẹlẹgẹ, 7,8-Dihydroxyflavone lulú ti ri lati mu iṣẹ iṣaro dara ati dinku awọn aiṣedeede ọpa ẹhin ni awọn awoṣe asin ti Fragile X Syndrome.

 

Ọtun Ẹjẹ

7,8-Dihydroxyflavone lulú ti a ti ri lati mu awọn aami aisan dara si ni awoṣe asin ti Rett syndrome-bi idagbasoke ti o lọra, iṣakoso iṣakoso iṣoro, ati awọn ọrọ ede.

 

şuga

7,8-Dihydroxyflavone lulú ti a ti ri lati dinku awọn iwa irẹwẹsi ninu awọn rodents.

 

afẹsodi

7,8-Dihydroxyflavone lulú ni a fihan lati munadoko ni idinku idunnu ati awọn ipa ere ti kokeni ninu awọn eku.

 

isanraju

7,8-Dihydroxyflavone lulú ni a ti rii lati ni anfani lati dinku iṣelọpọ ọra ati iṣelọpọ ọra ni awọn ẹkọ ẹranko.

 

ẹjẹ Ipa

7,8-Dihydroxyflavone lulú ti a ti ri lati ṣe afihan idinku ninu titẹ ẹjẹ nigba ti a fi sii. Awọn abere ẹnu ni anfani lati dinku titẹ ẹjẹ, ṣugbọn ko ṣe pataki ni akawe si nigbati 7,8-Dihydroxyflavone lulú ti fun ni awọn fọọmu itasi.

 

Ogbo awọ

7,8-Dihydroxyflavone lulú ti a ti ri lati dinku igbona, mu iṣelọpọ collagen pọ, ati mu awọn ipele enzymu antioxidant sii ninu awọn awọ ara eniyan ti ogbo.

 

akàn

7,8-Dihydroxyflavone lulú ni a ti rii pe o munadoko ninu pipa awọn sẹẹli alakan squamous oral ati akàn ara ti a mọ ni Melanoma ninu awọn ẹkọ satelaiti. Sibẹsibẹ, ọpọlọpọ awọn iwadii si tun nilo lati wa si awọn ipinnu eyikeyi, paapaa ninu eniyan.

 

Bawo ni lati gba 7,8-Dihydroxyflavone afikun?| Elo ni tropoflavin lulú yẹ ki Mo mu?

7,8-Dihydroxyflavone Doseji

Ko si awọn iwadii ile-iwosan ati awọn idanwo ti a ṣe lori eniyan bi ti bayi. Nitorinaa, iwọn lilo ailewu ti 7,8-Dihydroxyflavone lulú ko tun mọ ninu eniyan.

Iwọn lilo ti o wọpọ julọ ni awọn afikun ti o wa ni iṣowo jẹ 10 – 30 mg fun ọjọ kan. Sibẹsibẹ, o yẹ ki o ṣayẹwo pẹlu dokita rẹ ṣaaju ki o to bẹrẹ mu afikun.

 

7,8-Dihydroxyflavone ẹgbẹ ipa  

Bi ko si awọn idanwo ile-iwosan pẹlu eniyan ti a ti ṣe, awọn okunfa ewu ati awọn ipa ẹgbẹ ti 7, 8-Dihydroxyflavone jẹ aimọ. Alaye eyikeyi lori ailewu tabi awọn ipa ẹgbẹ jẹ lati iwadii ti a ṣe lori awọn awoṣe ẹranko. Sibẹsibẹ, ninu awọn olumulo ti o ti mu 7, 8-Dihydroxyflavone, awọn ipa wọnyi ni a ṣe akiyesi:

  • Aṣeju pupọ
  • Miiwu
  • Dizziness
  • Nikan
  • Irritability
  •   Iṣoro sùn

O tun ṣe akiyesi pe 7,8-Dihydroxyflavone lulú le ṣe ajọṣepọ pẹlu awọn oogun oogun miiran. 7, 8-Dihydroxyflavone jẹ ifaseyin gaan pẹlu awọn ohun elo miiran ati awọn agbo ogun. A ti rii ẹri lati daba ipa 7,8-Dihydroxyflavone ni yiyipada iṣe ti awọn enzymu ẹdọ CYP450. Eyi le yi ọna ti awọn oogun miiran ṣiṣẹ. Nitorinaa, o jẹ ailewu nigbagbogbo lati kan si dokita, paapaa ti o ba wa lori awọn oogun oogun.

 

7,Awọn orisun ounjẹ 8-Dihydroxyflavone – Bii o ṣe le ṣe afikun 7,8-Dihydroxyflavone nipa ti ara?

7,8-Dihydroxyflavone ṣubu labẹ idile flavonoid, eyiti o jẹ ẹgbẹ kan ti awọn nkan kemikali ti o nwaye nipa ti ara pẹlu awọn ẹya phenolic oniyipada. Awọn orisun ounjẹ ọlọrọ ni 7, 8-Dihydroxyflavone pẹlu tii alawọ ewe, kikan, soy, turmeric, ẹyin, kofi, blueberries, àjàrà ati chocolate dudu. Sibẹsibẹ, lati gba abajade to dara julọ lati 7,8-dihydroxyflavone, lati fa lati awọn ounjẹ wọnyi kii yoo jẹ ọna ti o dara julọ, ọna ti o taara diẹ sii ni lati mu awọn afikun 7,8-dihydroxyflavone. Wa olupese 7,8-dihydroxyflavone lulú ti o dara julọ, o le wa nibi. Ati ra 7,8-dihydroxyflavone lulú osunwon yoo gba owo to dara julọ.

 

Agbeyewo ti 7,8-Dihydroxyflavone

Ko si awọn iwadii ile-iwosan eyikeyi ninu eniyan nipa 7,8-dhf. Sibẹsibẹ, awọn ijinlẹ ẹranko ti fihan pe o munadoko ati rere. Awọn idanwo ile-iwosan ni awọn awoṣe ẹranko ti fihan pe 7,8-Dihydroxyflavone lulú ni ọpọlọpọ awọn anfani ni imudarasi iranti, aabo awọn sẹẹli ọpọlọ ati titọju iṣẹ ọpọlọ.

Awọn eniyan ti n gba o ni awọn ipa ẹgbẹ ti o kere pupọ ti o royin bii apọju, aisimi, dizziness, ríru, irritability ati wahala sisùn.

Pupọ diẹ sii iwadi ni a tun nilo lati pari awọn anfani gangan ati awọn ewu ti 7,8-Dihydroxyflavone lulú ninu eniyan.

 

ti o dara ju 7,8-Dihydroxyflavone lulú olupese / Nibo ni lati ra 7,8-Dihydroxyflavone lulú olopobobo?

Ọpọlọpọ 7 8-dihydroxyflavone wa fun tita lori laini. 7,8-Dihydroxyflavone lulú le ṣee ra lori ayelujara nipasẹ ọpọlọpọ awọn iÿë ati awọn ọna abawọle. O le ra ni awọn iwọn ti o baamu fun ọ. Ifẹ si 7,8-Dihydroxyflavone lulú ni iye pupọ le ṣe iranlọwọ fun ọ pẹlu awọn inawo gbogbogbo.

Nigbati o ba n wa lati ra afikun 7,8-Dihydroxyflavone lulú, o ṣe pataki lati wo daradara nipasẹ 7,8-Dihydroxyflavone lulú awọn olupese ati awọn ẹri wọn. Ibẹwo onsite lati rii ilana iṣelọpọ le rii daju pe awọn itọnisọna ailewu to dara ati awọn ilana iṣelọpọ ni atẹle lakoko iṣelọpọ.

Nitorina, didara ọja naa gbọdọ wa ni idaniloju ṣaaju ki o to pari si rira 7,8-Dihydroxyflavone lulú.

 

Awọn Ibeere Nigbagbogbo (FAQs) Nipa 7, 8-Dihydroxyflavone (7, 8-DHF), tabi Tropoflavin

Njẹ Tropoflavin jẹ Nootropic? 

Nootropics ti wa ni tun mo bi smati oloro. Oogun nootropic kan / akopọ ṣe ilọsiwaju iṣẹ imọ tabi iṣẹ ọpọlọ. Awọn idanwo ile-iwosan ni awọn ẹranko ti daba pe Tropoflavin le jẹ aṣoju nootropic. Sibẹsibẹ, ko si ẹri ipari ati pe a tun nilo iwadi diẹ sii.

Ninu eniyan, ko si idanwo ile-iwosan ti a ṣe titi di oni pẹlu 7,8-Dihydroxyflavone lulú. Nitorina ko ṣee ṣe lati sọ boya 7,8-Dihydroxyflavone lulú ni eyikeyi iṣẹ nootropic ninu eniyan.

 

Kí nìdí ra 7,8-Dihydroxyflavone lulú fun ilera ọpọlọ ti o dara julọ?

7,8-Dihydroxyflavone lulú ti han lati ni awọn anfani pupọ. Pẹlu iwadi ti o pọju ati awọn idanwo iwosan ti a ṣe ni awọn ẹranko, 7,8-Dihydroxyflavone lulú ni a ri lati ni ipa ti o dara lori iranti ati ẹkọ, atunṣe ọpọlọ, neuroprotection, egboogi-igbona, ibanujẹ, afẹsodi, isanraju, titẹ ẹjẹ ati awọ-ara.

7,8-Dihydroxyflavone lulú tun jẹ agbara diẹ sii ju BDNF ti o nwaye nipa ti ara ni ara wa. Nibẹ fun,

 

Kini Iyatọ Laarin 7, 8-Dihydroxyflavone ati BDNF?   

BDNF jẹ iṣelọpọ nipa ti ara ninu ara rẹ lakoko ti o jẹ pe 7,8-Dihydroxyflavone lulú wa ninu awọn eya ọgbin diẹ. 7,8-Dihydroxyflavone lulú jẹ bayi iṣelọpọ iṣelọpọ ati jẹun fun ọpọlọpọ awọn ipa ti o dara lori ọpọlọ.

7,8-Dihydroxyflavone lulú ti a ti ri lati ni idaji-aye to gun ati agbara si eyi ti a fiwe si BDNF. 7,8-Dihydroxyflavone lulú tun le wọ inu ọpọlọ nitori iwọn ti o kere pupọ.

 

Bii o ṣe le mu afikun 7, 8-Dihydroxyflavone lati gba abajade to dara julọ? 

Lọwọlọwọ ko si awọn ẹkọ eniyan lori 7,8-Dihydroxyflavone lulú fun itọkasi si iwọn lilo oogun. Pupọ julọ awọn iṣiro jẹ isunmọ ni mathematiki lati iwadii ninu awọn eku. Pupọ julọ ti iwadii ẹranko ti a ṣe fihan awọn abajade rere ni awọn fọọmu injectable. Pẹlu iwọn lilo ẹnu pẹlu 7,8-Dihydroxyflavone lulú, awọn abajade ni a rii, sibẹsibẹ, wọn jẹ afiwera ti o kere si pataki.

Niwọn igba ti awọn idanwo eniyan ko ti ṣe, o nira lati sọ asọye lori iwọn lilo eniyan. Ijumọsọrọ pẹlu dokita le ṣe iranlọwọ lati ṣalaye eyi.

 

Ṣe Tropoflavin Ṣe atilẹyin Pipadanu iwuwo?  

Awọn idanwo ile-iwosan ati iwadii ti ni anfani lati fihan pe 7,8-Dihydroxyflavone lulú fa pipadanu iwuwo, paapaa ni awọn eku abo. Awọn awari wọnyi ko ti ri ninu eniyan nitori ko si iwadi ti a ṣe titi di oni.

Evi tun wa

dence ti o ni imọran 7,8-Dihydroxyflavone lulú le fa pipadanu iwuwo nipasẹ imudarasi atilẹyin gbogbogbo fun kokoro arun ikun.

 

Ṣe Tropoflavin fa Isonu Irun (tabi Ṣe atilẹyin Idagba Irun)? 

Titi di oni, ko si ẹri lati daba pe 7,8-Dihydroxyflavone lulú fa irun irun ni eyikeyi fọọmu. Diẹ ninu awọn ijinlẹ ẹranko ti fihan pe BDNF ati awọn agbo ogun miiran le ni ipa ninu ṣiṣakoso idagbasoke irun. Iwadi nla ati awọn idanwo ile-iwosan tun nilo ninu eniyan lati sọ asọye lori ọran naa.

 

Bawo ni lati fipamọ Dihydroxyflavone (Tropoflavin)?  

Gẹgẹbi oogun miiran, o jẹ ailewu nigbagbogbo lati tọju 7,8-Dihydroxyflavone lulú kuro ni arọwọto awọn ọmọde. O jẹ apẹrẹ lati tọju rẹ kuro ni imọlẹ orun taara ati pe o gbọdọ wa ni ipamọ ni itura, ibi gbigbẹ.

 

Ṣe 7-8 Dihydroxyflavone mu ibanujẹ pọ si?

7,8-Dihydroxyflavone lulú ti ri pe o munadoko ni idinku awọn iwa irẹwẹsi ni awọn eku. Ko si data ile-iwosan wa bi ti bayi fun 7,8-Dihydroxyflavone lulú ipa ninu ibanujẹ ninu eniyan.

 

jo

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[11] 7,8-dihydroxyflavone, agonist olugba TrkB kan, dina ailagbara iranti aye igba pipẹ ti o fa nipasẹ aapọn aibikita ninu awọn eku. Raül Andero, Núria Daviu, Rosa Maria Escorihuela, Roser Nadal, Antonio Armario

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[14] 7,8-Dihydroxyflavone attenuates itusilẹ ti awọn olulaja pro-iredodo ati awọn cytokines ninu awọn sẹẹli BV2 microglial ti lipopolysaccharide nipasẹ titẹkuro ti NF-κB ati awọn ipa ọna ifihan MAPK. Hye Young Park, Cheol Park, Hye Jin Hwan, Byung Woo Kim, Gi-Young Kim, Cheol Min Kim, Nam Deuk Kim, Yung Hyun Choi.

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[16] 7,8-dihydroxyflavone Ameliorates Awọn aipe Mọto Nipasẹ Itumọ α-synuclein ati Wahala Oxidative ninu Awoṣe Asin ti MPTP ti Arun Pakinsini. Xiao-Huan Li, Chun-Fang Dai, Long Chen, Wei-Tao Zhou, Hui-Li Han, Zhi-Fang Dong.

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[17]7,8-Dihydroxyflavone ṣe ilọsiwaju iṣẹ mọto ati pe o mu iwalaaye neuronal mọto kekere ni awoṣe asin ti sclerosis ita gbangba amyotrophic.

Orhan Tansel Korkmaz, Nurgul Aytan, Isabel Carreras, Ji-Kyung Choi, Neil W Kowall, Bruce G Jenkins, Alpaslan Dedeoglu,

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Mali Jiang, Qi Peng, Xia Liu, Jing Jin, Zhipeng Hou, Jiangyang Zhang, Susumu Mori, Christopher A Ross, Keqiang Ye, Wenzhen Duan

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