Epo Tita Galantamine Hydrobromide (69353-21-5)

December 27, 2018

Galantamine Hydrobromide lulú jẹ oludena cholinesterase ti o ti lo lati yiyipada …… ..


ipo: Ni Ifilelẹ Production
Apapọ: 25kg / Ilu
agbara: 1290kg / osù

Epo Tita Galantamine Hydrobromide (69353-21-5) fidio

 

Epo Tita Galantamine Hydrobromide (69353-21-5) Apejuwe

Raw Galantamine Hydrobromide lulú jẹ benzazepine ti a mu lati norbelladine. O wa ni GALANTHUS ati AMARYLLIDACEAE miiran. O jẹ oludaniloju cholineterase ti a ti lo lati yiyipada awọn iṣan ti iṣan ti GALLAMINE TRIETHIODIDE ati TUBOCURARINE ati pe a ti ṣe ayẹwo bi itọju fun ALZHEIMER DISAIASE ati awọn ailera aifọwọyi miiran.

Raw Galantamine Hydrobromide lulú jẹ fọọmu iyọ iyọ hydrobromide ti galantamine, alkaloid ti ile-iwe giga ti a gba ni iṣelọpọ tabi nipa ti ara lati awọn isusu ati awọn ododo ti Narcissus ati ọpọlọpọ pupọ iran miiran ti idile Amaryllidaceae pẹlu anticholinesterase ati awọn iṣẹ imudara neurocognitive. Galantamine ni idije ati yiyipada idiwọ acetylcholinesterase, nitorinaa npọ si ifọkansi ati imudarasi iṣẹ ti acetylcholine (Ach). Ni afikun, galantamine jẹ ligand fun awọn olugba acetylcholine nicotinic, eyiti o le mu ifasilẹ presynaptic ti Ach ṣiṣẹ ki o mu awọn olugba postsynaptic ṣiṣẹ. Oluranlowo yii le mu ilọsiwaju iṣan-ara iṣan ṣiṣẹ ni irẹlẹ ati irẹjẹ aisan Alzheimer ati pe o le dinku awọn aami aiṣan ti o fa ifamọra ti o ṣe igbelaruge ifasẹyin siga.

Epo Galantamine Hydrobromide lulú (69353-21-5) Sawọn ilana

ọja orukọ Raw Galantamine Hydrobromide powder
Orukọ Kemikali Galantamin; Akọọlẹ; Galanthamine
Galanthamine Hydrobromide; Lycoremine; Nivalin
Nivaline; Razadyne; Reminyl
Galanthamine hydrobromide; Ekun Galantamine Hydrobromide lulú; 1953-04-4; Reminyl; Galanthamine (hydrobromide);
brand NAti Ko si data wa
Oko Drug Awọn oluranlowo Arun Alzheimer, cholestterase inhibitor
CAS Number 69353-21-5
InChIKey QORVDGQLPPAFRS-XPSHAMGMSA-N
molikula Fagbalagba C17H22BrNO3
molikula Wmẹjọ 368.271 g / mol
Ibi Monoisotopic 367.078 g / mol
Isun Point  126-127 deg C
Gilara Point Ko si data wa
Idaji Ida-Omi Imukuro idaji-aye: 7 wakati
Awọ White ri to
Solubility  Ti o ṣe itọka ni omi gbona; laisi iṣelọpọ ninu oti, acetone, chloroform. Sogbin kekere ni benzene, ether.
Sdidiṣi Tti otutu  -20 ° C
Application oludaniloju cholineterase; ogun

 

aise Hydrobromide Galantamine lulú (69353-21-5) Apejuwe

Galantamine Hydrobromide jẹ fọọmu iyọ hydrobromide ti galantamine, alkaloid ti ile-iwe giga ti a gba ni iṣelọpọ tabi nipa ti ara lati awọn isusu ati awọn ododo ti Narcissus ati ọpọlọpọ pupọ iran miiran ti idile Amaryllidaceae pẹlu awọn egboogi-ila-ila-ara ati awọn iṣẹ imudara-imọ-ara. Galantamine ni idije ati yiyipada idiwọ acetylcholinesterase, nitorinaa npọ si ifọkansi ati imudarasi iṣẹ ti acetylcholine (Ach). Ni afikun, galantamine jẹ ligand fun awọn olugba acetylcholine nicotinic, eyiti o le mu ifasilẹ presynaptic ti Ach ṣiṣẹ ki o mu awọn olugba postsynaptic ṣiṣẹ. Oluranlowo yii le mu ilọsiwaju iṣan-ara iṣan ṣiṣẹ ni irẹlẹ ati irẹjẹ aisan Alzheimer ati pe o le dinku awọn aami aiṣan ti o fa ifamọra ti o ṣe igbelaruge ifasẹyin siga.

Hydrobromide Galantamine lulú (69353-21-5) Iseto ti Ise?

Galantamine jẹ alkaloid phenanthrene ati iparọ, onidena acetylcholinesterase ifigagbaga. Ko ṣe ibatan pẹlu igbekalẹ si awọn onidena acetylcholinesterase miiran. Ilana ti Galantamine gbekalẹ ti iṣe pẹlu idinamọ iparọ ti acetylcholinesterase, eyiti o ṣe idiwọ hydrolysis ti acetycholine, ti o yori si ifọkansi pọsi ti acetylcholine ni awọn synapses cholinergic. Galantamine tun ṣe asopọ allosterically pẹlu awọn olugba acetylcholine nicotinic ati pe o le ṣee ṣe agbara ti iṣe ti agonists (bii acetylcholine) ni awọn olugba wọnyi.

anfani of Hydrobromide Galantamine lulú (69353-21-5)

  • Ṣiṣe Iwọn Ti Iṣẹ
  • Din iredodo
  • Ṣe Antioxidant
  • Ṣe Ṣe Idabobo Awọn Oje
  • Ṣe Ṣe abojuto Àtọgbẹ
  • Ṣe Ṣe Itọju Ibaju
  • Induces Lucid Dreaming
  • Le Ṣe Iwọn Awọn aami aisan ti Autism
  • Ṣe iranlọwọ lati ṣe itọju Schizophrenia
  • Ṣiṣe Àrùn Àrùn
  • Le Ṣe iranlọwọ fun ọ lati din siga
  • Idaabobo lodi si Ẹtan ọpọlọ

niyanju Hydrobromide Galantamine lulú (69353-21-5) Ẹsẹ

Agbara Vitamini ti Galantamine 16 mg / ọjọ jẹ abawọn ti o dara julọ fun awọn alaisan pẹlu AD alaiwọn, bi a ṣe rii ipa ti o ni iru pẹlu iwọn lilo 24 mg / ọjọ. Sibẹsibẹ, awọn alaisan ti o ni AD mode dada lati ni anfani diẹ lati galantamine 24 mg / ọjọ.

ẹgbẹ ipa of Hydrobromide Galantamine lulú (69353-21-5)

Awọn ipa ẹgbẹ ti o wọpọ ti Galantamine Hydrobromide lulú pẹlu awọn iṣọn-ara iṣan ati ailera, awọn iṣẹlẹ aarun-atẹgun, awọn iṣoro awọ-ara, ati aito ito. Gbigba awọn abere giga ti Galantamine laisi gbigbe soke laiyara le tun fa awọn ala alẹ ati aibalẹ.

Ni afikun si awọn ipa wọnyi, ibaraẹnisọrọ Galantamine pẹlu awọn oògùn miiran le fa awọn iṣoro ilera. A ni imọran lati dẹkun lilo Galantamine nigbati o ba mu awọn oogun miiran ti a ti mu nipasẹ ọna ọna ẹdọ kanna (eto cytochrome aisan).

A dupẹ, julọ ninu awọn igbelaruge ẹgbẹ ti o loke jẹ toje ati ki o le ṣee yee fun pẹlu dosing.