Urolitin A 8-Methyl Eteri

April 8, 2021

Urolithins jẹ awọn metabolites ti apọju ti ellagic acid ti a fa jade lati awọn ellagitannins. Ninu eniyan ellagitannins ni a yipada nipasẹ ikun microflora sinu ellagic acid eyiti a tun yipada siwaju si urolithins A, urolithin B, urolithin C ati urolithin D ninu awọn ifun titobi.

Urolithin A 8-Methyl Ether (35233-17-1) fidio

 

Urolithin A 8-Methyl Ether (35233-17-1)ni pato

ọja orukọ Urolithin A lulú 8-Methyl Ether
Orukọ Kemikali 3-hydroxy-8-methoxy-6H-benzo [c] chromen-6-ọkan;

3-hydroxy-8-methoxybenzo [c] chromen-6-ọkan;

35233-17-1;

MLS001049096;

SMR000386929;

ChemDiv3_002724;

Urolitin A 8-Methyl Eteri;

CAS Number 35233-17-1
InChIKey IGJLBTGXYKPECW-UHFFFAOYSA-N
molikula Fagbalagba C14H10O4
molikula Wmẹjọ 242.23
Ibi Monoisotopic 242.057909 g / mol
yo ojuami 242 ° C (Solv: acid acetic (64-19-7))
farabale ojuami  479.9 ± 38.0 ° C (Asọtẹlẹ)
Daridaju 1.375 ± 0.06 g / cm3 (Sọtẹlẹ)
Idaji Ida-Omi N / A
Awọ Imọlẹ Alagara si Okun Osan Giga Dudu pupọ
Solubility  Acetone (Diẹ, Sonicated) DMSO (Diẹ, Sonicated), Methanol (Diẹ)
Sdidiṣi Tti otutu  Hygroscopic, -20 ° C Grẹi, Labẹ inert atmosphere
Application Urolithin A 8-Methyl Ether jẹ agbedemeji ninu iṣelọpọ ti Urolithin A (U847000), iṣelọpọ nla ti Ellagitannin ati ṣafihan awọn egboogi-iredodo ati awọn ohun-ini ẹda ara ẹni.

 

Reference

[1] Espín, Juan Carlos; Larrosa, Mar; García-Conesa, María Teresa; Tomás-Barberán, Francisco (2013). “Pataki ti Ẹmi ti Urolithins, Gut Microbial Ellagic Acid-Derived Metabolites: Ẹri Titi Jina”. Imudara ti o da lori Ẹri ati Oogun Idakeji. 2013: 270418. ṣe: 1155/2013/270418. ISSN1741-427X. PMC 3679724. PMID 23781257.

[2] Ryu, Dongryeol; Mouchiroud, Laurent; Andreux, Pénélope A; Katsyuba, Elena; Moullan, Norman; Nicolet-dit-Félix, Amandine A; Williams, Evan G; Jha, Pooja; Sasso, Giuseppe Lo (2016). “Urolithin A n fa mitophagy mu ki o fa gigun gigun ni C. elegans ati mu iṣẹ iṣan pọ si ninu awọn eku”. Oogun Iseda. 22 (8): 879–888. ṣe: 1038 / nm.4132. PMID 27400265.

[3] Ishimoto, Hidekazu; Shibata, Mari; Myojin, Yuki; Ito, Hideyuki; Sugimoto, Yukio; Tai, Akihiro; Hatano, Tsutomu (2011). "Ni vivo egboogi-iredodo ati awọn ohun elo ẹda ara ẹni ti ellagitannin metabolite urolithin A" (PDF). Bioorganic & Awọn lẹta Kemistri Oogun. 21 (19): 5901-5904. ṣe: 1016 / j.bmcl.2011.07.086. PMID 21843938.

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