Urolithin A （1143-70-0） fidio
Urolithin A （1143-70-0）ni pato
| ọja orukọ | Urolithin A lulú |
| Orukọ Kemikali | 3,8-dihydroxy-6H-benzo [c] chromen-6-ọkan;
3,8-Dihydroxy-6H-dibenzo (b, d) pyran-6-ọkan; 3,8-Dihydroxyurolithin; 3,8-dihydroxybenzo [c] chromen-6-ọkan; 6H-Dibenzo [b, d] pyran-6-ọkan, 3,8-dihydroxy-; 3,8-Hydroxydibenzo-alpha-pyrone; |
| CAS Number | 1143-70-0 |
| InChIKey | RIUPLDUFZCXCHM-UHFFFAOYSA-N |
| SMILES | C1=CC2=C(C=C1O)C(=O)OC3=C2C=CC(=C3)O |
| molikula Fagbalagba | C13H8O4 |
| molikula Wmẹjọ | 228.2 g / mol |
| Ibi Monoisotopic | 228.042259 g / mol |
| yo ojuami | 340-345 ° C |
| farabale ojuami | 527.9 ± 43.0 ° C (Asọtẹlẹ) |
| Oju filaṣi | 214.2ºC |
| Idaji Ida-Omi | Urolithin A wa ninu ito titi di wakati 48 lẹhin lilo oje pomegranate. |
| Awọ | Funfun si alagara |
| Solubility | DMSO: 20 mg / mL, ko o |
| Sdidiṣi Tti otutu | 2-8 ° C |
| Application | Ti a lo bi afikun ounjẹ ati ọja alatako, le ṣee lo lati dinku iredodo ati ja akàn; |
Reference:
[1] Garcia-Muñoz, Cristina; Vaillant, Fabrice (2014-12-02). "Apejọ ti iṣelọpọ ti Ellagitannins: Awọn Imuwa fun Ilera, ati Awọn Iwadi Iwadi fun Awọn ounjẹ Iṣẹ-ṣiṣe Alailẹgbẹ". Awọn atunyẹwo Lominu ni Imọ Ounje ati Ounjẹ. 54 (12): 1584–1598. ṣe: 10.1080 / 10408398.2011.644643. ISSN 1040-8398. PMID 24580560. S2CID 5387712.
[2] Ryu, D. et al. Urolithin A n fa mitophagy mu ki o fa gigun igbesi aye ni C. elegans ati mu iṣẹ iṣan pọ si ninu awọn eku. Nat. Med. 22, 879–888 (2016).
[3] "FDA GRAS ṣe akiyesi GRN NỌ 791: urolithin A". US Ounje ati Oogun ipinfunni. 20 Oṣù Kejìlá 2018. Ti gba pada ni 25 August 2020.
[4] Singh, A.; Andreux, P.; Blanco-Bose, W.; Ryu, D.; Aebischer, P.; Auwerx, J.; Rinsch, C. (2017-07-01). “Urolithin A ti a nṣakoso ẹnu jẹ ailewu ati ṣe atunṣe iṣan ati awọn oniṣowo bioococ mitochondrial ni agbalagba”. Innovation in Ogbo. 1 (suppl_1): 1223–
[5] Heilman, Jacqueline; Andreux, Pénélope; Tran, Nga; Rinsch, Chris; Blanco-Bose, William (2017). “Ayẹwo aabo ti urolithin A, ijẹẹmu ti iṣelọpọ nipasẹ iṣan eniyan microbiota lori gbigbe ti ijẹẹmu ti awọn ellagitannins ti ọgbin ati ellagic acid”. Ounjẹ ati Kemikali Toxicology. 108 (Pt A): 289– doi: 10.1016 / j.fct.2017.07.050. PMID 28757461.
